LACTIC ACID

PRODUCT IDENTIFICATION

50-21-5, 79-33-4 (L), 10326-41-7 (D)

CH₃CH(OH)COOH

90.08

H.S. CODE

TOXICITY

CLASSIFICATION

Food acidity regulator, Preservative, Plant growth regulator

EXTRA NOTES

PHYSICAL AND CHEMICAL PROPERTIES

-0.72 (octanol-water)

REFRACTIVE INDEX

NFPA RATINGS

AUTOIGNITION

112 C

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - Lactic acid

PubChem Compound Summary - Lactic acid

Drug Bank -  Lactic acid

KEGG (Kyoto Encyclopedia of Genes and Genomes) -  Lactic acid

http://www.ebi.ac.uk/ -  Lactic acid

http://www.ncbi.nlm.nih.gov/ -  Lactic acid

Human Metabolome Database - Lactic acid

Material Safety Data Sheet

Local:
Lactic acid (chemically, alpha or 2-Hydroxypropionic acid) takes roles in metabolic processes in the body; in red blood and in skeletal muscle tissues as a product of glucose and glycogen metabolism. Lactic acid is an "alpha hydroxy acid: which has a hydroxyl group on the carbon atom next to the acid group. If the hydroxy group is on the second carbon next to the acid group, it is called beta-hydroxy acid. Lactic acid is converted in vivo to pyruvic acid (an alpha keto acid) which occurs as an intermediate product in carbohydrate and protein metabolism in the body. Lactic acid occurs as two optical isomers since the central carbon atom is bound to four different groups; a dextro and a levo form ( or an inactive racemic mixture of the two); only the levo form takes part in animal metabolism. Lactic acid is present  in sour milk and dairy products such as cheese, yogurt, and  koumiss, leban, wines.  Lactic acid causes tooth decay since lactic acid bacteria operates in the mouth. Although it can be prepared by chemical synthesis, production of lactic acid by fermentation of glucose and other sugar substances in the presence of alkaline such as lime or calcium carbonate is a less expensive method. The six-carbon glucose molecule is broken down to two molecules of the three-carbon compounds (lactic acid), during this anaerobic condition. Synthetic lactic acid is used commercially in tanning leather and dyeing wool; as a flavouring agent and preservative in food processing and carbonated beverages; and as a raw material in making plastics, solvents, inks, and lacquers; as a catalyst in numerous chemical processes. Lactic Acid is available as aqueous solutions of various concentrations, usually 22 - 85 percent (pure lactic acid is a colourless, crystalline substance.) Some examples of lactates (salts or esters of lactic acid) are:

• Ammonium Lactate (NH₄C₃H₅O₃, CAS RN: 515-98-0): clear to yellow, syrupy liquid used in in electroplating, in finishing leather and as humectant for food, pharmaceutical, and cosmetics.
• Butyl Lactate (CH₃CHOHCOOC₄H₉, CAS RN:138-22-7): a clear liquid: nontoxic, miscible with many solvents; used as a solvent for varnish, lacquers, resins and gums, used in making paints, inks, dry cleaning fluid, flavoring and as a chemical intermediate.
• Calcium Lactate Pentahydrate [Ca(C₃H₅O₃)₂·5H₂O, CAS RN: 814-80-2] : white crystals; soluble in water; used as a calcium source; administered orally in the treatment of calcium deficiency; as a blood coagulant.
• Ethyl Lactate   (CH₃CHOHCOOC₂H₅, CAS RN: 97-64-3): clear liquid with mild odur; boiling point 154 C; miscible with alcohols, ketones, esters, and hydrocarbons as well as with water; used in pharmaceutical preparations, feed additive, as a flavoring ( odor description: sweet butter, coconut, fruity, creamy dairy, butterscotch) and as a solvent for cellulose compounds such as nitrocellulose, cellulose acetate, and cellulose ethers.
• Magnesium Lactate Trihydrate [Mg(C₃H₅O₃)₂·3H₂O, CAS RN: 18917-93-6 ]: white crystals with bitter taste; soluble in water, slightly soluble in alcohol; used in medicine and as an electrolyte replenisher.
• Manganese Lactate Trihydrate [Mn(C₃H₅O₃)₂·3H₂O]: pale red crystals; insoluble in water and alcohol; used in medicine.
• Mercuric Lactate [Hg(C₃H₅O₃)₂]: poisonous white powder that decomposes when heated; soluble in water; used in medicine.
• Methyl Lactate (CH₃CHCHCOOCH₃): clear liquid with mild odur; boiling point 145 C; miscible with alcohols, ketones, esters, and hydrocarbons as well as with water; used in pharmaceutical preparations, feed additive, as a flavoring and as a solvent for cellulose compounds such as nitrocellulose, cellulose acetate, and cellulose ethers.
• Sodium Lactate (CH₃CHOHCOONa, CAS RN: 72-17-3) clear to yellow, hygroscopic syrupy liquid; soluble in water; melting point 17 C; used in medicine, in antifreeze, and hygroscopic agent and as a corrosion inhibitor.
• Zinc Lactate (Zn(C₃H₅O₃)₂·2H₂O, CAS RN: 16039-53-5): white crystals; used as an additive in toothpaste and food; preparation of drugs.

EXAMPLES OF NATURALLY OCCURRING CARBOXYLIC ACIDS
(excluding fatty acids)

FCC IV 80 GRADE

APPEARANCE

PURITY

80% min

20ppm max

0.01% max

0.1% max

Fe

10ppm max

As

1ppm max

HEAVY METALS

10ppm max

HAZARD OVERVIEW

OSHA Hazards: Irritant

GHS

Danger

PICTOGRAMS

HAZARD STATEMENTS

H315-H318-H338

P STATEMENTS

P-261-P280-P302 + P352-P305 + P351 + P338

RISK PHRASES

37/38

SAFETY PHRASES

41